CBD to combat drug-resistant bacteria?
There’s a growing run out of tribes at the end of the risk of antibiotic-resistant bacteria, are urgently needed alternative strategies to protect us from such a dangerous pathogens and to prevent the spread of antibiotic resistance. A combination of antibiotics and Cannabidiol (CBD) enhanced the effect of the antibiotics. This causes less antibiotics for treatment are needed.
In the current investigation of the University of Southern Denmark, it was found that the combination of CBD and antibiotic, and has a strengthening effect. The results of the study were published in the English scientific journal “Scientific Reports”.
Bacteria become resistant to antibiotics
Since the discovery of Penicillin in 1928 by Sir Alexander Fleming, antibiotics have saved millions of people from deadly infections. Unfortunately, bacteria have developed mechanisms to protect themselves from the effects of antibiotics. They have become resistant.
How to antibiotics reinforced
As fewer and fewer antibiotics to treat resistant bacterial infections are available, there is a danger, in a pre-antibiotic Era to fall back. In the search for alternative strategies to the special attention of the researchers was directed compounds on so-called Helpers. Such helper compounds are non-antibiotic Compounds, which can improve the effectiveness of antibiotics.
Cannabidiol enhances the effect of antibiotics?
It has been suggested that Cannabidiol (CBD) could act as such a helper connection. In the case of Cannabidiol is a Cannabinoid from the cannabis plant. The new study was able to demonstrate such a reinforcing effect of antibiotics through the CBD.
Combination required less antibiotics for treatment
When CBD was combined with antibiotics, could be observed with a stronger effect than treatment with antibiotics alone, according to the research team. A certain number of bacteria needed to kill so less antibiotics. In the study, CBD was used to enhance the effect of the antibiotic Bacitracin against the bacterium Staphylococcus aureus.
Treatment of infections with antibiotic-resistant bacteria.
Multidrug-resistant strains of this pathogen have already been spread around the world. In some countries, the treatment of bacterial infections with these resistant bacteria is already very problematic. As to be expected, will extend of this Problem in the future. A combination of CBD and antibiotics could provide a novel treatment of infections with antibiotic-resistant bacteria.
What are the implications of a combination of antibiotics and CBD?
As the bacterium Staphylococcus aureus was treated with a combination of CBD and antibiotics, were observed various effects. The bacteria were no longer able to divide normally. The Expression of certain key genes (cell division and Autolysis genes) in bacteria was reduced and the bacterial membrane was unstable, report the researchers in a press release.
Excessive use of antibiotics must be avoided
The researchers suggest that the excessive use of antibiotics is resistance, the main cause for the present antibiotics. If an antibiotic is combined with a helper substance, which enhances the effect of the antibiotic, would be needed less antibiotic to achieve the same effect. This could help in the future, less antibiotics would be needed and fewer resistant bacteria to emerge. (as)